![]() ![]() So when people say the laboratory was the source of infection, they mean something human-generated that was not intended. The second possibility is that something happened involving a human accident-either scientists brought the virus from nature into the laboratory and accidentally infected someone who then spread it, or the virus was changed in some way in the lab that then led to the infection of a human and it spread from there. ![]() So that’s certainly a very legitimate concern. In the large outbreak of SARS-CoV-1, for example, civets were determined to be the source animal for the spillover. ![]() The basis for the first one-that a virus circulating in the animal population “spilled over” into humans-is that about 75% of emerging infectious diseases are found to have spilled over from an animal. What are the merits of each of those theories? Three years into the COVID-19 pandemic, we are still debating whether it started with a natural spillover event or a lab leak. ![]()
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